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Table 2 Age-adjusted IRR for the association between total IgG level with clinical malaria

From: Antibody levels to multiple malaria vaccine candidate antigens in relation to clinical malaria episodes in children in the Kasena-Nankana district of Northern Ghana

Antibody

Antigen

Crude IRR (95%CI)

IRR adjusted for age

(95%CI)

P-value for adjusted IRR

IgG

GLURP-R0

0.76 (0.67, 0.86)

0.85 (0.75, 0.96)

0.01

 

GLURP-R2

0.65 (0.55, 0.78)

0.77 (0.65, 0.91)

<0.01

 

MSP1-3D7

0.72 (0.61, 0.85)

0.79 (0.69, 0.91)

<0.01

 

MSP1-FVO

0.81 (0.63, 1.06)

0.73 (0.58, 0.93)

0.01

 

MSP3-3D7

0.75 (0.63, 0.89)

0.86 (0.74, 1.01)

0.06

 

AMA1-3D7

0.72 (0.63, 0.82)

0.80 (0.71, 0.91)

<0.01

 

AMA1-FVO

0.72 (0.62, 0.83)

0.81 (0.71, 0.93)

<0.01

 

AMA1-LR32

0.74 (0.64, 0.85)

0.85 (0.74, 0.96)

0.01

 

EBA-175

0.66 (0.56, 0.78)

0.81 (0.68, 0.97)

0.02

 

LSA-1

0.79 (0.64, 0.98)

0.89 (0.73, 1.09)

0.26

  1. IRRs indicate the ratio of malaria incidence rates associated with a twofold increase in antibody level