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Table 6 Results of Primary Multiplicative Incidence Model on Risk of Hg < 8.5 g/dL

From: Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine

Variable

Risk Ratio

Two-sided p-value

 

(95% CI)

(NS > 0.25)

Vaccination with 80ug

2.01 (1.26, 3.20)

0.0035

AMA1-C1

  

Age at time of anaemia event*

0.45 (0.29, 0.70)

0.0004

Baseline Hg > = 10 g/dL

0.78 (0.52, 1.17)

NS

Baseline Hg < 10 g/dL

4.26 (2.72, 6.69)

< 0.0001

Male Sex

0.74 (0.46, 1.17)

NS

HbS

0.83 (0.42, 1.61)

NS

HbC

0.96 (0.43, 2.15)

NS

G6PD deficiency

2.27 (0.85, 6.04)

NS

α-thalassaemia heterozygote

0.71 (0.41, 1.23)

NS

α-thalassaemia homozygote

0.41 (0.12, 1.45)

NS

  1. * Risk ratio is reduced by a factor of 0.452 for each year older