Figure 3From: Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in miceRelationships amongst four important pharmacological parameters for quinoline methanols were evaluated for evidence of correlations. A possible linear correlation between maximum and free brain concentration is evident on visual inspection of the data, and was confirmed mathematically (r2 = 0.89, P < 0.0001). There was no relationship evident between the other variables. Data are presented in a log format for ease of visualization. The correlation coefficient was calculated based on raw (not log transformed) data.Back to article page