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Table 2 Frequency of positive ELISpot assays conducted in urban and rural populations using long (LP) and short (SP) peptides

From: Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults

 

No. assays

Total

No. positive assays/all assays

Total

Pop.

LP

SP

LP+SP

LP

SP

LP+SP

Urban (n = 13)

76

52

128

11/76 (14.5%)

3/52 (5.8%)

14/128 (10.9%)

Rural (n = 17)

93

44

137

22/93 (23.7%)

5/44 (11.4%)

27/137 (19.7%)

Total

169

96

265

33/169 (19.5%)

8/96 (8.3%)

41/265 (15.5%)

  1. Six mixtures and 3 single peptides (9 stimulants) of long (DR-binding) or 6 mixtures and 12 single of short (HLA A or B-restricted) peptides (18 stimulants) were tested with HLA-matched urban and rural volunteers. The number of assays that were performed and the number of assays that were positive are shown and expressed as per cent of total assays. The sequences of the peptides, and how they were combined, are shown in Additional File 4.