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Table 7 Summary of assays with positive ELISpot activities using statistical Methods 1, 2 and 3

From: Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults

 

CSP

AMA1

Method

Assays

No. Positive

Cp1*

Assays

No. Positive

Ap7and9**

>Med.

324

138 (42.6%)

30/138 (21.7%)

420

236 (56.2%)

53/201 (26.3%)

1

324

30 (9.3%)

16/30 (53.0%)

420

94 (22.4%)

40/84 (47.6%)

2

324

17 (5.2%)

13/17 (76.5%)

420

62 (14.8%)

34/57 (60.0%)

3

324

10 (3.1%)

9/10 (90%)

420

41 (9.8%)

29/36 (80.1%)

  1. ELISpot activities >medium controls were analysed using Methods 1, 2 and 3 (see Methods) and the positive activities for each method are shown. The numbers of Cp1 are for all volunteers tested, Ap7+Ap9 excluding v1001 who responded to different peptide pools. * Proportion of positive assays that are positive by Cp1; ** Proportion of positive assays that are positive by Ap7 or Ap9 excluding v1001.