Table 3 Prevalence of resistance associated single nucleotide polymorphisms in pfdhfr and pfdhps from southern Pakistan
Pfdhfr | Pfdhps | |||||||
|---|---|---|---|---|---|---|---|---|
n | 51I | 59R | 108N | n | 436A | 437G | 540E | |
Karachi | 161 | 16 (0.1) | 144 (0.89) | 159 (0.99) | 170 | 1 (0.006) | 99 (0.58) | 3 (0.02) |
Sindh | 48 | 2 (0.04) | 44 (0.92) | 47 (0.98) | 51 | 0 | 13 (0.26) | 0 |
Baluchistan | 9 | 0 | 9 (1) | 9 (1) | 10 | 0 | 6 (0.60) | 0 |
Total | 218 | 18 (0.08)* | 197 (0.90)§ | 215 (0.99) | 231 | 1 (0.004) | 118 (0.51) | 3 (0.01)† |