Table 4 Prevalence of pfdhfr- pfdhps haplotypes in P. falciparum isolates from southern Pakistan.
Pfdhfr N51I, C59R, S108N, I164L Pfdhps S436A, A437G, K540E* | No. of isolates | ||||
|---|---|---|---|---|---|
No. of mutations | Karachi (n = 158) | Sindh (n = 47) | Baluchistan (n = 9) | Total (n = 214) | |
NCSI-SAK | 0 | - | 1 (0.02) | - | 1 (0.005) |
NRN I-SG K | 3 | 80 (0.51) | 9 (0.19) | 5 (0.55) | 94 (0.44) |
NRN I-SAK | 2 | 55 (0.35) | 33 (0.70) | 4 (0.45) | 92 (0.43) |
IRN I-SG K | 4 | 1 (0.006) | - | - | 1 (0.005) |
IRN I-SGE | 5 | 1 (0.006) | - | - | 1 (0.005) |
IRN I-SAK | 3 | 4 (0.03) | 1 (0.02) | - | 5 (0.02) |
I CN I-SAK | 2 | 5 (0.03) | - | - | 5 (0.02) |
I CN I-SG K | 3 | 3 (0.02) | 1 (0.02) | - | 4 (0.02) |
I CN I-SGE | 4 | 2 (0.01) | - | - | 2 (0.01) |
NCN I-SAK | 1 | 3 (0.02) | - | - | 3 (0.01) |
NCN I-SG K | 2 | 2 (0.01) | 2 (0.04) | - | 4 (0.02) |
NCSI-A AK | 1 | 1 (0.006) | - | - | 1(0.005) |
NCSI-SG K | 1 | 1 (0.006) | - | - | 1(0.005) |