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Table 4 Gene Ontology terms enriched following addition of dehydrobrachylaenolide at 2 and 6 hours post-treatment (at p < 0.05).

From: In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling

Time post treatment

Biological process

Molecular function

p-value

Corrected p-value

(false discovery rate, p < 0.05)

 

chromatin silencing

 

0.00056108

0.0026184

 

dephosphorylation

 

0.0016571

0.0069599

 

electron transport

 

0.018276

0.036552

 

DNA replication

 

0.027838

0.048717

2 hpt

 

chromatin binding

0.00076337

0.0049195

  

histone binding

0.0018045

0.0095146

  

pepsin A activity

0.019635

0.049515

 

chromatin silencing

 

0.0022313

0.0096688

 

dephosphorylation

 

0.0064848

0.018577

 

tRNA modification

 

0.012566

0.029149

6 hpt

 

chromatin binding

0.00047321

0.0031305

  

actin binding

0.003905

0.011994

  

sugar metabolism

0.0082591

0.022196

  

histone binding

0.0082591

0.022196