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Table 1 The nucleotide and amino acid substitutions at dhfr gene screened for by PCR-SSOP

From: The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination

Codon

50

51

59

108

164

Wild type

Cys (C)

TGT

Asn (N)

AAT

AAC

Cys (C)

TGT

Ser (S) AGC

Ile (I)

ATA

Mutant

Arg (R)

CGT

Ile (I)

ATT

Arg (R)

CGT

Asn (N) AAC

Thr (T)

ACC

Leu (L)

TTA