Table 2 Ratio based on the chloroquine-susceptible reference clone 3D7 (strain IC₅₀/3D7 IC₅₀) of chloroquine, quinine, mefloquine, monodesethylamodiaquine, lumefantrine, pyrimethamine, atovaquone, dihydroartemisinin and doxycycline against 36 strains of Plasmodium falciparum under controlled incubator conditions (10% O₂) and Genbag^® conditions (15% O₂)

Chloroquine

10

6.88

4.15-11.41

0.40

55.80

<0.0001

15

4.80

3.09-7.45

0.60

38.30

Quinine

10

2.44

1.90-3.13

0.65

7.39

0.2418

15

2.63

2.04-3.40

0.66

7.24

Mefloquine

10

0.72

0.63-0.82

0.39

1.64

<0.0001

15

0.91

0.81-1.03

0.49

2.089

Monodesethylamodiaquine

10

2.59

1.80-3.72

0.29

23.69

0.5948

15

2.52

1.73-3.67

0.32

28.33

Lumefantrine

10

0.90

0.74-1.09

0.27

2.45

0.0119

15

0.81

0.67-0.98

0.28

2.76

Pyrimethamine

10

27.31

8.75-85.21

1.00

1703

0.0835

15

18.01

5.51-58.82

1.00

1494

Atovaquone

10

0.88

0.59-1.31

0.07

5.20

0.9187

15

0.89

0.67-1.19

0.08

4.96

Dihydroartemisinin

10

1.53

1.27-1.85

0.74

6.79

0.0006

15

1.31

1.04-1.64

0.54

7.94

Doxycycline

10

1.21

1.09-1.35

0.85

2.90

0.0002

15

1.37

1.21-1.55

0.80

3.11