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Table 2 Sensitivity of detection for dried blood specimens at different parasite densities and storage times

From: Dried Plasmodium falciparum-infected samples as positive controls for malaria rapid diagnostic tests

  

Sensitivity

  

Week 1

Week 4

Week 12

RDT1

200 parasites /μl

100

100

100

 

2,000 parasites /μl

100

100

100

RDT2 Pf (Pan)

200 parasites /μl

100 (22)†

100 (75)†

100 (12.5)†

 

2,000 parasites /μl

100 (100)

100 (100)

100 (80)#

RDT3

200 parasites /μl

100

100

100

 

2,000 parasites /μl

100

100

100

RDT4

200 parasites /μl

100

100

100

 

2,000 parasites /μl

100

100

100

RDT5

200 parasites /μl

55.5‡

12.5‡

37.5

 

2,000 parasites /μl

100

100

100

RDT6 Pf (Pan)

200 parasites /μl

89 (67)

100 (33)

75 (0)*

 

2,000 parasites /μl

100 (89)

100 (86)

100 (80)

RDT7

200 parasites /μl

100

100

87.5#

 

2,000 parasites /μl

100

100

100

RDT8

200 parasites /μl

100

100

100

 

2,000 parasites /μl

100

100

100

RDT9

200 parasites /μl

100

100

87.5#

 

2,000 parasites /μl

100

100

100

RDT10 Pf (Pan)

200 parasites /μl

100 (0 )*

100 (0 )*

100 (33)

 

2,000 parasites /μl

100 (100)

100 (100)

100 (100)

  1. † Pan band was weakly reactive for two of three parasites at baseline.
  2. ‡ Weakly reactive for all three parasites at baseline.
  3. * Pan test negative for two of three parasites and weakly reactive for the one positive parasite at baseline.
  4. # Reactivity lost for one sample stored at 35°C.