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Figure 1 | Malaria Journal

Figure 1

From: Pharmacokinetic profiles of artesunate following multiple intravenous doses of 2, 4, and 8 mg/kg in healthy volunteers: Phase 1b study

Figure 1

Mean plasma concentration-time profiles of artesunate (AS, left) and dihydroartemisinin (DHA, right), an active metabolite of AS, measured by LC-MS/MS (markers) and computer pharmacokinetic fitting curves (solid-line) following multiple intravenous dosage with 2 min short-term infusion of AS at 2 (top), 4 (middle), and 8 (bottom) mg/kg in healthy volunteers. (n = 6 for each dose cohort).

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Malaria Journal

ISSN: 1475-2875

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