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Table 3 Prevalence of pfdhfr (codons 51, 59, 108 and 164) and pfdhps (codons 436, 437, 540 and 581) mutants

From: Therapeutic efficacy of artesunate in the treatment of uncomplicated Plasmodium falciparum malaria and anti-malarial, drug-resistance marker polymorphisms in populations near the China-Myanmar border

Gene

Mutation

Number

Frequency (%)

pfdhfr

Quadruple mutants

22 (58)

38.0

Triple mutants 51/59/108

9 (58)

15.5

Triple mutants 59/108/164

21 (58)

36.2

Double mutants 59/108

6 (58)

10.3

pfdhps

Quadruple mutants

13 (55)

23.6

Triple mutants 436/437/581

8 (55)

14.5

Double mutants 436/437

2 (55)

3.6

Double mutants 436/540

1 (55)

1.8

Double mutants 437/540

28 (55)

50.9

Double mutants 437/581

3 (55)

5.5