Skip to main content

Table 5 Diagnostic performances of the CareStart Malaria™ test and the VIKIA Malaria Ag Pf/Pan™ test at several reading times (10, 15, 20, 30 and 60 min) for detection of Plasmodium spp. in field study patients, Cambodia, 2011

From: Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections

 

RDT diagnostic performance

Sensitivity (95%CI)

Specificity (95%CI)

PPV (95% CI)

NPV (95% CI)

CareStart Malaria RDT

Pf

93.4% (87.4-97.1%)

98.6% (97.3-99.40%)

93.4% (87.4-97.10%)

98.6% (97.3-99.4%)

Non-Pf

85.8% (80.7-90.0%)

99.1% (98.0-99.7%)

97.6% (94.4-99.2%)

94.5% (92.4-96.2%)

VIKIA Malaria Ag Pf/Pan RDT - Reading time 10 min.

Pf

89.7% (82.6-94.6%)

99.3% (98.3-99.8%)

96.3% (90.8-99.0%)

97.9% (96.4-98.9%)

Non-Pf

61.5% (54.9-67.8%)

99.5% (98.5-99.9%)

97.9% (94.1-99.6%)

86.4% (83.6-89.0%)

VIKIA Malaria Ag Pf/Pan RDT - Reading time 15 min.

Pf

92.5% (86.2-96.5%)

99.1% (98.0-99.7%)

95.7% (90.2-98.6%)

98.4% (97.1-99.3%)

Non-Pf

77.0% (71.1-82.2%)

99.5% (98.5-99.9%)

98.4% (95.3-99.7%)

91.4% (88.9-93.5%)

VIKIA Malaria Ag Pf/Pan RDT - Reading time 20 min.

Pf

93.4% (87.4-97.1%)

98.6% (97.3-99.40%)

93.4% (87.4-97.10%)

98.6% (97.3-99.4%)

Non-Pf

81.1% (75.5-85.9%)

98.9% (97.7-99.6%)

96.9% (93.4-98.9%)

92.8% (90.5-94.7%)

VIKIA Malaria Ag Pf/Pan RDT - Reading time 30 min.

Pf

93.4% (87.4-97.1%)

98.6% (97.3-99.40%)

93.4% (87.4-97.10%)

98.6% (97.3-99.4%)

Non-Pf

82.8% (77.4-87.4%)

98.9% (97.7-99.6%)

97.0% (93.6-98.9%)

93.4% (91.2-95.3%)

VIKIA Malaria Ag Pf/Pan RDT - Reading time 60 min.

Pf

94.2% (88.4-97.6%)

98.1% (96.6-99.0%)

91.2% (84.8-95.5%)

98.8% (97.5-99.5%)

Non-Pf

82.7% (77.3-87.4%)

98.9% (97.7-99.6%)

97.0% (93.5-98.9%)

93.4% (91.1-95.2%)

  1. Pf: P. falciparum; Non-Pf: Plasmodium non-falciparum.
  2. PPV: Positive predictive value; NPV: Negative predictive value.