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Table 1 Patient demographic, clinical and laboratory features including ex vivo parasite development in preparation for static binding assays

From: Cytoadherence and virulence - the case of Plasmodium knowlesi malaria

 

Patient details

Study reference

P0002

P0006

P0009

P0010

P0011

Age

16

47

28

27

37

Sex

M

F

M

M

M

% Parasitaemia

0.4

0.8

7

0.8

1.3

Fever duration (days)

7

5

6

5

4

Axillary Temp°C

37.5

38.5

39.2

38.7

38

Mean Art BP mmHg

79

96

70

86

77

Pulse per min

62

96

96

103

94

Haemoglobin g/dL

13.4

13.2

12.3

14.1

12.8

Platelets/uL

93,000

106,000

19,000

39,000

65,000

White cells/uL

6600

6700

6900

7500

4600

Sodium mmol/L

133

131

120

132

131

Potassium mmol/L

3.7

4.9

3.6

3.3

3.9

Chloride mmol/L

100

99

92

101

100

Total bilirubin umol/L

20.6

15.7

38.4

9.7

48.9

Conjugated bilirubin umol/L

5

12.8

23

4

32.6

Alkaline phosphatase U/L

100

62

87

131

233

Alanine aminotransferase U/L

28

21

43

35

68

Asparagine aminotransferase UL

17

30

118

23

22

Blood urea mmol/L

4.4

5.7

44.7

6

8.8

Serum creatinine umol/L

-

78

600

59

133

 

Static binding assay details

% Mature Troph/Schizonts before ex vivo culture

25

40

17

10

10

Hours ex-vivo culture

10

14.5

10

10

12

% Mature Troph/Schizonts at start of assay

75

50

91

63

50