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Table 4 Specificity of anti-CSP repeats ELISA using sera pre-incubated with different antigens

From: Validation of an enzyme-linked immunosorbent assay for the quantification of human IgG directed against the repeat region of the circumsporozoite protein of the parasite Plasmodium falciparum

Sample Code

Concentration of anti-CSP repeats antibody (EU/ml) Inhibited with:

% inhibition

R32LR

AMA-1

HBsAg

CONTROL*

R32LR

AMA-1

HBsAg

1

37

70

69

76

51.3

7.9

9.2

2

80

134

141

138

42.0

2.9

−2.2

3

56

97

102

105

46.7

7.6

2.9

4

97

156

160

162

40.1

3.7

1.2

5

146

249

243

250

41.6

0.4

2.8

6

51

89

98

97

47.4

8.2

−1.0

7

84

148

167

167

49.7

11.4

0.0

8

124

213

223

217

42.9

1.8

−2.8

9

121

222

235

222

45.5

0.0

−5.9

Mean

    

45.2

4.9

0.5

  1. AMA-1, apical membrane antigen-1; CSP, circumsporozoite protein; HBsAg, hepatitis B surface antigen.
  2. * control: no inhibitory antigen used (co-incubation with diluent).