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Table 3 Linear regression model

From: Naturally acquired immune responses to malaria vaccine candidate antigens MSP3 and GLURP in Guahibo and Piaroa indigenous communities of the Venezuelan Amazon

 

MSP3

GLURP

β

95% low

CI for β high

p

β

95% low

CI for β high

p

Age in years

1,02

1,01

1,02

<0.001

1,01

1,00

1,01

0.019

Sex

1,07

0,92

1,26

0.373

1,10

0,90

1,36

0.354

Possession mosquito net

1,12

0,77

1,63

0.556

2,52

1,54

4,13

<0.001

Constant use of ITN1

1,18

0,89

1,56

0.256

1,30

0,90

1,88

0.168

Malaria episode (ever)

1,10

0,92

1,32

0.309

0,99

0,78

1,26

0.947

Malaria episode (12 m2)

1,37

1,08

1,73

0.009

1,34

0,98

1,82

0.066

Ethnic group

1,31

1,10

1,54

0.002

1,26

1,01

1,57

0.041

  1. Explanation: As antibody titres are not expected to be Gaussian distributed the models calculated with the decadic logarithms of the measured IgG levels. Results were then delogarithmized. Age in years showed significant influence for each year of age. Females' trend to have higher antibody levels resulted not statistically significant. The possession of a mosquito net caused no significant coefficient for MSP3, but for GLURP, whereas every night usage of a mosquito-net during the last 30 days entailed no significant influence antibodies. The coefficients for self-reported malaria episodes during the whole lifetime were not significant, unlike those for the incidence in the previous 12 months (MSP3). Ethnic background affected the linear equation with significant coefficients for both, MSP3 and GLURP
  2. 1 Insecticide treated net
  3. 2 Within the last 12 months