Table 1 Characteristics of the study groups, median (range) for (age, parasite density, IgG and IgG subclasses) regarding pregnancy duration
Study groups variables | First trimester | Second trimester | Third trimester | P value |
|---|---|---|---|---|
Malaria-free control n=58 (48%) | 13 (22.4%) | 13 (22.4%) | 32 (55.2%) | <0.001 |
Asymptomatic Malaria n=62 (52%) | 34 (54.8%) | 20 (32.3%) | 8 (12.9%) | |
FcγRIIa genotypes | ||||
R/R131 n=41 (%) | 22 (53.7%) | 17 (41.5%) | 2 (4.9%) | <0.001 |
R/H131 n=41 (%) | 20 (48.8%) | 11 (26.8%) | 10 (24.4%) | |
H/H131 n=38 (%) | 5 (13.2%) | 5 (13.2%) | 28 (73.7%) | |
FcγRIIa alleles | ||||
R 131 allele | 0.68 | 0.68 | 0.18 | 0.004 |
H 131 allele | 0.32 | 0.32 | 0.82 | |
Median (range) for: | ||||
Age/years | 21 (18–26) | 22 (18–26) | 23 (18–26) | 0.046 |
Parasite density/μl | 1600 (250–2000) | 1400 (510–2000) | 1050 (250–2000) | 0.007 |
Specific antibody for AMA-1 | ||||
IgG | 1.28 (0.28- 6.04) | 1.28 (0.50- 7.30) | 2.76 (0.29- 6.90) | 0.003 |
IgG1 | 0.59 (0.11- 21–95) | 5.30 (0.16- 22.27) | 5.43 (0.05- 32.89) | 0.180 |
IgG2 | 0.04 (0.02- 5.64) | 2.11 (0.02- 5.73) | 2.16 (0.02- 6.10) | 0.040 |
IgG3 | 0.52 (0.01- 37.94) | 8.33 (0.12- 39.45) | 8.39 (0.09- 46.00) | 0.185 |
IgG4 | 0.02 (0.01- 2.62) | 0.59 (0.01- 3.24) | 0.61 (0.01- 2.01) | 0.514 |