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Table 3 Parasite clearance times according to mixed model analysis of 84 malaria patients receiving parenteral anti-malarial treatment

From: Manual blood exchange transfusion does not significantly contribute to parasite clearance in artesunate-treated individuals with imported severe Plasmodium falciparum malaria

Treatment mode

Quinine (n = 59)

Artesunate (n = 25)

Adjunct treatment

No exchange transfusion (n = 37)

Exchange transfusion (n = 22)

No exchange transfusion (n = 9)

Exchange transfusion (n = 16)

PCT 50% (h)

8.0 (7.2-8.8)

7.3 (6.5-8.2)

5.0 (4.4-5.6)

4.7 (4.2-5.2)

PCT 90% (h)

26.6 (23.9-29.4)

24.3 (20.7-28.0)

16.6 (14.6-18.7)

15.7 (14.1-17.3)

PCT 95% (h)

34.6 (31.0-38.2)

31.7 (28.8-34.5)

21.6 (17.5-25.7)

20.4 (18.3-22.5)

PCT 99% (h)

53.2 (47.7-58.8)

48.7 (43.0-54.3)

33.2 (30.5-35.9)

31.4 (28.1-34.6)

  1. Data are given as mean (95% confidence interval).
  2. Three of 87 patients were excluded from analysis because of an initial parasitaemia lower than 1,000 parasites per μL (Quinine n = 1) or because the last parasitaemia exceeded 1,000 parasites per μL (Quinine plus ET n = 1; artesunate n = 1), as defined by Flegg et al.[17].