Figure 2

The distribution across 28 sequential cases of vessel sequestration ( as measured by % of vessels parasitized ) across six sites within the brain are shown as stacked bars ( maximum = 600 represented 100% of vessels parasitized × 6 sites ). Cases are ordered by mean % of vessels parasitized. The dotted horizontal line represents the overall cut off for “cerebral malaria” (23.3% × 6 sites = 139.8) and demonstrates that, for total brain quantification, there is a clear cut-off between controls (non-cerebral malaria, cases 1–13) and cases (cerebral malaria, cases 14–28).