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Figure 2 | Malaria Journal

Figure 2

From: Host immune constraints on malaria transmission: insights from population biology of within-host parasites

Figure 2

Time series of parasite density for two simulated infections with P. falciparum . (A) Blood density of different stages of the parasite as a function of time in an infection for which the host clears all parasite forms. (B) Clearance rate of various immune responses as a function of time since primary release, same infection as (A). (C) Blood density of different stages of the parasite as a function of time in an infection for which the host dies of anemia. (D) Clearance rate of various host immune responses as a function of time since primary release, same infection as (C). (E) Color code used for (A) and (C) for parasite forms. (F) Color code used for (B) and (D) for host immune modalities. The initial time is at the start of primary release of merozoites from the liver. The model parameters used for these two examples are given in Table 1.

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