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Figure 7 | Malaria Journal

Figure 7

From: Host immune constraints on malaria transmission: insights from population biology of within-host parasites

Figure 7

Effects of gametocyte-specific antibodies in simulated infection on gametocyte duration. Results are from simulated infections in which the host cleared all parasites within three years from primary release of merozoites, and which also made mature gametocytes. The ratio of the duration of mature gametocytes, Dur MG to the duration of the asexual forms, Dur Asx was binned by Dur Asx , and also by a measure of the ability of the antibody response to clear their target, I S Gcy . The horizontal length of an individual block shows the bin size in Dur Asx , and the vertical extent of a block show the bin size in IS Gcy . Results are only shown for bins that contained 10 or more simulations. (A) Dur MG /Dur Asx for simulated P. falciparum infections in which antibodies attacked mature gametocytes and not immature forms. (B) Dur MG /Dur Asx for simulated P. falciparum infections in which antibodies attacked immature gametocytes and not mature forms. (C) Same as (A), except for simulated P. vivax infections. (D) Same as (B), except for simulated P. vivax infections. (E) Color code used for Dur MG /Dur Asx .

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