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Table 4 Statistical value of clinical signs, association of clinical signs and malaria tests (QBC and HRP2-based RDT) for the diagnosis of malaria, according to the results of the thick and thin Giemsa-stained blood films, considered to be the gold standard method (with 95% confidence intervals for sensibility and specificity)

From: Malaria relevance and diagnosis in febrile Burkina Faso travellers: a prospective study

 

Sensibility

Specificity

Positive predictive value

Negative predictive value

Isolated fever

78.3%

71.3%

44.3%

91.9%

[68.5 – 88.0]

[65.6 – 77.1]

Fever present on examination

31.9%

85.2%

38.6%

81.1%

[20.9 – 42.9]

[80.7 – 89.8]

Isolated fever present on examination

26.1%

96.2%

66.7%

81.7%

[15.7 – 36.5]

[93.8 – 98.6]

Digestive symptoms

13.0%

62.9%

9.3%

71.3%

[5.1 – 21.0]

[57.2 – 69.4]

QBC

98.6%

99.6%

98.6%

99.6%

 

[9.7 – 100]

[98.8 – 100]

  

HRP2

84.0%

98.0%

92.0%

95.0%

(for P. falciparum)

[75.4 – 92.7]

[96.7 – 99.9]