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Table 2 Sensitivity, specificity, predictive values of microscopy and Paracheck- Pf ® with PCR as gold standard

From: Performance of microscopy and RDTs in the context of a malaria prevalence survey in Angola: a comparison using PCR as the gold standard

  

PCR

PCR

Sensitivity %

Specificity %

PPV %

NPV %

Positive

Negative

(CI95)

(CI95)

(CI95)

(CI95)

(n = 525)

(n = 2,782)

    

Microscopy

Positive

315

210

60.0

92.5

60.0

92.5

(n = 525)

(55.8-64.2)

(91.4-93.4)

(55.7-64.2)

(91.4-93.4)

Negative

210

2,572

(n = 2,782)

Paracheck- Pf®

Positive

382

158

72.8

94.3

70.7

94.8

(n = 540)

(68.7-76.5)

(93.4-95.2)

(66.7-74.6)

(93.9-95.6)

Negative

143

2,624

(n = 2,767)

 
 

P-value*

<0.0001

<0.0001

<0.0001

<0.0001

  1. PPV: positive predictive value; NPV: negative predictive value.
  2. CI95: 95% confidence interval.
  3. *Obtained from McNemar test (sensitivity, specificity) / Weighted generalized score Chi-square test (PPV, NPV).