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Table 3 Sensitivity, specificity and predictive values of microscopy and Paracheck-Pf ® by age group with PCR as gold standard

From: Performance of microscopy and RDTs in the context of a malaria prevalence survey in Angola: a comparison using PCR as the gold standard

 

Age

Sensitivity %

Specificity %

PPV %

NPV %

(CI95)

(CI95)

(CI95)

(CI95)

Microscopy

0 - 5

68.4

92.7

67.8

92.9

(61.9-74.5)

(90.9-94.2)

(61.3-73.9)

(91.1-94.4)

6 -15

60.6

91.6

62.6

91.0

(53.7-67.2)

(89.7-93.4)

(55.6-69.3)

(88.9-92.7)

> 15

36.8

93.0

34.8

93.6

(26.7-47.8)

(91.1-94.6)

(25.2-45.4)

(91.7-95.1)

P-value*

<0.0001

0.5032

<0.0001

0.0897

Paracheck- Pf®

0 - 5

80.4

93.5

73.6

95.5

(74.7-85.4)

(91.8-95.0)

(67.6-79.0)

(94.0-96.7)

6 - 15

76.5

93.3

72.4

94.5

(70.3-82.1)

(91.5-94.8)

(66.1-78.2)

(92.8-95.9)

> 15

43.7

96.4

55.1

94.4

(33.1-54.7)

(94.9-97.5)

(42.6-67.1)

(92.7-95.9)

P-value*

<0.0001

0.0064

0.0088

0.4946

  1. Age shown in years; PPV: positive predictive value; NPV: negative predictive value.
  2. CI95: 95% confidence interval.
  3. *Obtained from Pearson Chi-squared test.