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Table 1 Cytokine levels in the semi-immune mice strains and uninfected controls

From: Anti-erythropoietin antibody levels and its association with anaemia in different strains of semi-immune mice infected with Plasmodium berghei ANKA

Cytokine (pg/ml)

Mouse strains (number)

P value*

Balb/c (8)

B6 (4)

CBA (6)

NZW (4)

Uninfected control (4)

IL6 (SD)

6692.0

513.1a

136.7b

464.1d

71.60c

0.0001

(4443.0)

(757.9)

(76.8)

(664.6)

(30.63)

IL17 (SD)

6052.0

205.3a

4.59b

89.7d

4.05c

< 0.0001

(4202.0)

(323.0)

(0.71)

(121.0)

(0.5)

IL10 (SD)

13.97

12.51

23.14

16.31

4.625

0.08

(12.67)

(5.9)

(33.3)

(10.15)

(1.33)

INFγ (SD)

6785.0

715.7

93.74b

413.9d

6.5c

0.001

(4805.0)

(1218.0)

(83.7)

(799.8)

(0.38)

TNF (SD)

54.86

202.5

16.24

18.65

16.15

0.07

(35.4)

(410.4)

(1.08)

(3.835)

(3.85)

TNF:IL10 (SD)

4.5

1.7

1.5

1.5

4.0

0.002

(1.0)#

(0.6)

(0.7)

(0.9)

(2.4)

  1. Blood was harvested for serum at minimum Hb. Values are pooled data of two separate experiments. *P values done by ANOVA was performed on the log10 transformed data. Analysis was done by ANOVA with Tukey’s post test. a, b, c, d Statistically lower than Balb/c. #Significantly higher than the other strains.