Figure 7
Cross-reactivity screening of antibodies measured on native protein on the pRBC surface. Analysis of surface reactivity of a panel of 15 parasite strains or isolates with goat IgG or rat sera generated against NTS-DBL1α-domains of IT4var9, PAvarO, DBL1αS1.2var1, 3d7var5.2, PAvarO (mixed) and DBL1αS1.2var1, 3d7var5.2, PAvarO (sequential). Empty squares: no reactivity; dark grey squares: reactivity of more than 10× above background; grey squares: reactivity of 5-10× above background; light grey squares: reactivity of 2–5× above background nd: not done. Star indicates parasites with a rosetting phenotype.