Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000–2011

Table 2 Trends in molecular genotypes and in vitro susceptibility for P. falciparum isolates

Slopes of prevalence in *Pfcrt76T*
	2000-2011		2004-2011
	Slope (95% CI)	P value	Slope (95% CI)	P value
Senegal	−0.167 [−0.209; -0.125]	<10^-3	−0.182 [−0.264; -0.102]	<10^-3
Mali	−0.009 [−0.052; 0.034]	0.72	−0.102 [−0.178; -0.027]	0.03
Ivory Coast	−0.146 [−0.183; -0.111]	<10^-3	−0.265 [−0.325; -0.207]	<10^-3
Cameroon	−0.090 [−0.130; -0.050]	<10^-3	−0.106 [−0.172; -0.041]	<10^-3
Slopes of IC ₅₀ values for CQ
Senegal	−0.081 [−0.130; -0.032]	<10^-3	−0.123 [−0.220; -0.026]	<10^-3
Mali	−0.042 [−0.090; 0.007]	0.02	−0.098 [−0.167; -0.030]	<10^-3
Ivory Coast	−0.057 [−0.093; -0.021]	<10^-3	−0.120 [−0.177; -0.063]	<10^-3
Cameroon	−0.055 [−0.089; -0.020]	<10^-3	−0.100 [−0.154; -0.046]	<10^-3

Slopes of prevalence in Pfcrt76T and slopes of IC50 values from patients returning to France from Senegal, Mali, Ivory Coast, and Cameroon, between 2000–2011 and 2004–2011 (after CQ withdrawal).

ISSN: 1475-2875