Figure 1

Short-term aversive memory impairment without locomotor and exploratory changes following Plasmodium berghei ANKA infection. Aversive memory, locomotor and exploratory activities measurement of P. berghei-infected mice on day 5 and 6 post-infection (pi) and of control group in the step-down inhibitory avoidance test (a-c) and in the open field (d-e). (a) Latency in seconds during training session (5 pi) in the step-down inhibitory avoidance test; (b) Short-term memory analysed 1.5 hours after training session in the step-down inhibitory avoidance test; (c) Long-term memory analysed 24 hours (6 pi) after training session in the step-down inhibitory avoidance test; (d) number of crossings and (e) number of rearing episodes analysed on day 5 post-infection in the open field. Results are expressed as mean ± SEM and are representative of two independent experiments. Asterisk(s) indicate statistical differences, *p < 0.05.