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Table 1 Summary of the 13 included studies

From: Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Country

Years

Number patients

Sampling schedule

Counting method

DLM

Reference

Thick (WBC)

Thin (RBC)

 

Thailand1

2001-2010

3391

SS1

500

1000

16

Phyo et al.[20]

Thailand2

2008

40

SS3

200

1000

16

Dondorp et al.[4]

Thailand3

2009-2010

80

SS2

200

1000

16

Das et al.[21]

Mali

2010

261

SS1

300

ND

25

Lopera-Mesa et al.[19]

Cambodia1

2007-2008

59

SS2

200

1000

16

Dondorp et al.[4]

Cambodia2

2008-2010

79

SS2

200

1000

16

Das et al.[21]

Cambodia3

2009

79

SS1

200

ND

15

Amaratunga et al.[18]

Cambodia4

2010

98

SS1

200

ND

15

Amaratunga et al.[18]

Cambodia5

2010

30

SS1

200

ND

15

Amaratunga et al.[18]

Cambodia6

2010

55

SS1

200

ND

15

Unpublished

Cambodia7

2008-2009

143

SS2

200

5000

14

Bethell et al.[24]

Kenya

2010-2011

171

SS2

  

30

Unpublished

Vietnam

2010-2011

166

SS1

400

1000

8

Hien et al.[25]

Total

 

4652

     
  1. SS1 = six-hourly until negative; SS2 = zero, two, four, six, eight and 12 hours, and then six-hourly until negative; SS3 = zero, four, eight and 12 hours, and then six-hourly until negative; ND = not done; DLM = detection limit of microscopy (in parasites per μL); RBC = red blood cells; WBC = white blood cells.