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Figure 6 | Malaria Journal

Figure 6

From: Haptoglobin phenotype prevalence and cytokine profiles during Plasmodium falciparum infection in Dogon and Fulani ethnic groups living in Mali

Figure 6

Cytokine profiles in supernatants from in vitro stimulation assays with Haptoglobin:Haemoglobin complexes. Isolated PBMCs were stimulated with Hp1-1:Hb or Hp2-2:Hb (both 10 μg/ml) for 24 hours and thereafter corresponding supernatants were collected and analysed for various cytokines. Levels of A) IL-1beta, B) IL-6, C) IL-8, D) IL-10, E) IL-12p70, F) TNF and G) IFN-γ from 11 independent experiments are shown. The boxes represent the lower quartile (25%) and the upper quartile (75%) with the middle line as the median. The whiskers indicate the 10 and 90% percentiles. Statistical analysis was done with Wilcoxon Signed ranktest.

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