Plasmodium falciparum clearance in clinical studies of artesunate-amodiaquine and comparator treatments in sub-Saharan Africa, 1999–2009

Zwang, Julien; Dorsey, Grant; Mårtensson, Andreas; d’Alessandro, Umberto; Ndiaye, Jean-Louis; Karema, Corine; Djimde, Abdoulaye; Brasseur, Philippe; Sirima, Sodiomon B; Olliaro, Piero

doi:10.1186/1475-2875-13-114

Table 2 Patients at enrolment

From: Plasmodium falciparum clearance in clinical studies of artesunate-amodiaquine and comparator treatments in sub-Saharan Africa, 1999–2009

Year	Site	Total	Under six years old		Treatment		Parasitaemia
			n	%	ASAQ (n)	Comparator (n)	μL	Anaemia (%)
2004	Angola-Caala 2004	137	137	100	69	68	29,180	28
2003	Angola-Kuito 2003	187	187	100	97	90	19,216	61
2008	Burkina faso - Nanoro 2008	810	810	100	295	515	20,831	83
2005	Burkina Faso Puytenga 2005	890	824	93	890	NA	15,210	76
2006	Cameroon 2006	166	79	48	110	56	24,627	8
2004	Congo-Kindamba 2004	298	298	100	101	197	25,890	64
2008	Gabon - 2008	226	226	100	80	146	22,265	69
1999	Gabon 1999	220	119	54	110	110	22,537	NA
2004	Guinee-Dabola 2004	220	220	100	110	110	37,493	73
1999	Kenya 1999	400	346	87	200	200	31,095	61
2009	Kenya 2009	54	0	0	54	NA	12,181	2
2009	Liberia 2009	1300	302	23	648	652	1,340	11
2006	Madagascar 2006	179	76	42	119	60	9,159	19
2004	Mali Bancouna 2004	753	714	95	252	501	15,468	44
2006	Mali Bougoula 2006	203	134	66	135	68	22,183	51
2008	Mozambique - Manhica 2008	420	420	100	210	210	39,023	62
2008	Nigeria - Afokang 2008	261	261	100	92	169	18,361	72
2008	Nigeria - Pamol 2008	233	233	100	82	151	18,177	73
2003	RDC Boende 2003	279	279	100	136	143	24,170	57
2002	Rwanda Mashesha 2002	122	122	100	61	61	14,729	45
2004	Rwanda Mashesha 2004	269	269	100	89	180	20,454	39
2002	Rwanda Rukara 2002	95	95	100	49	46	25,855	40
2004	Rwanda Rukara 2004	270	269	100	89	181	36,868	31
2002	Rwanda-Kicukiro 2002	91	91	100	48	43	13,457	31
2004	Rwanda-Kicukiro 2004	223	223	100	74	149	36,515	28
2000-5	Sen-Djembeye 2000-5	137	18	13	137		25,992	8
1999	Senegal 1999	321	123	38	160	161	40,386	NA
2006	Senegal 2006	392	11	3	264	128	7,991	47
2000-5	Sen-Mlomp 2000-5	723	74	10	723	NA	46,328	3
2000-5	Sen-Oussouye 2000-5	208	106	51	208	NA	19,142	NA
2004	Sierra Leone Kailahun 2004	126	126	100	126	NA	27,116	56
2003	South Sudan Nuba 2003	161	161	100	80	81	21,964	31
2003	Sudan Malakal 2003	269	269	100	134	135	22,881	86
2008	Uganda - Mbarara 2008	319	319	100	160	159	23,431	51
2003	Uganda Amudat 2003	212	212	100	106	106	18,410	49
2004	Uganda Tororo 2004	541	508	94	194	347	18502	71%
2005	Uganda Tororo 2005	408	388	95	204	204	21,480	40
2004	Uganda-Apac-2004	542	516	95	174	368	11,701	64
2004	Uganda-Arua-2004	534	509	95	174	360	23,927	63
2003	Uganda-Jinja-2003	543	370	68	189	354	34,337	40
2006	Uganda-Kampala-2006	730	358	49	242	488	10,581	11
2008	Zambia - Ndola 2008	245	245	100	85	160	36,401	85
2002	Zanzibar Kivunge 2002	297	296	100	148	149	16,500	78
2002	Zanzibar Micheweni 2002	105	105	100	54	51	16,777	87
	Total	15017	11550	77	7660	7357	16,964	50

Legend: NA, non-applicable.

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ISSN: 1475-2875

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