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Table 6 Mean value (standard deviation) of Apoptosis index and ratio (standard deviation) of expression of inflammation and hypoxia markers according to plasmodial species infecting the placenta

From: Submicroscopic infection of placenta by Plasmodium produces Th1/Th2 cytokine imbalance, inflammation and hypoxia in women from north-west Colombia

 

PM-a

PM + Pfa

PM + Pva

PM + mixed

P*

Apoptotic cells index

44.78 (2.15)

71.32 (4.45)

61.04 (5.96)

57.56 (3.06)

0.000

Fas

3.2 (0.84)

5.18 (2.11)

6.57 (1.61)

10.49 (2.09)

0.000

FasL

6.74 (1.16)

4.49 (2.47)

5.5 (2.82)

5.68 (2.3)

0.009

HIF

0.1 (0.22)

0.37 (0.66)

0.35 (0.47)

0.82 (2.97)

0.000

VEGF

0.05 (0.15)

0.09 (0.17)

0.06 (0.07)

0.09 (0.06)

0.412

COX1

0.43 (0.41)

6.64 (3.54)

5.22 (0.69)

5.9 (3.4)

0.000

COX2

0.24 (0.29)

2.45 (0.93)

2.71 (0.82)

2.19 (1.82)

0.000

  1. aPM- without placental malaria (n = 25); PM + Pf with placental infection by P. falciparum (n = 16); PM + Pv with placental infection by P. vivax (n = 6); PM + mixed with placental infection by both species (n = 3).
  2. *(Kruskal-Wallis).