From: Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort
Characteristics | First trimester | First half of second trimester | All trimesters |
---|---|---|---|
n = 602 | n = 1181 | n = 1783 | |
Mean age, (years)* | 25.7 (6.8; 14 – 49) | 25.9 (6.7; 13 – 46) | 25.8 (6.8; 13 – 49) |
Mean BMI* | 23.2 (3.9; 14.2 – 39.6) | 23.3 (3.6; 14.0 – 42.5) | 23.4 (3.7; 14.0 – 42.5) |
Mean gestational age, (weeks)* | 10.5 (2.6; 3 – 12) | 16.9 (1.5; 13 – 20) | 14.8 (3.7; 3 – 20) |
Gravidity# | |||
Primigravidae | 182 (30.0) | 377 (31.9) | 559 (31.4) |
Secundigravidae | 109 (18.0) | 227 (19.2) | 336 (18.8) |
3 – 4 pregnancies | 180 (29.6) | 315 (26.7) | 495 (27.8) |
≥ 5 pregnancies | 131 (21.4) | 262 (22.2) | 393 (22.0) |
Recruited sites# | |||
Health facility | 468 (22.3) | 973 (82.4) | 1441 (80.8) |
Home | 134 (77.7) | 208 (17.6) | 342 (19.2) |
Drinking alcohol# | 14 (2.7) | 27 (2.3) | 41 (2.3) |
Smoking cigarette# | 5 (0.8) | 2 (0.2) | 7 (0.4) |
Haemoglobin level (g/dl)* | 10.8 (1.5; 5.0 – 14.6) | 10.7 (1.5; 5.4 – 14.9) | 10.7 (1.5; 5.0 – 14.9) |
HIV status# | |||
Negative | 533 (88.5) | 1086 (92.0) | 1619 (90.8) |
Positive | 18 (3.0) | 46 (3.9) | 64 (3.6) |
No results | 51 (8.5) | 49 (4.1) | 100 (5.6) |
Syphilis test# | |||
Negative | 521 (86.5) | 1082 (91.6) | 1603 (89.9) |
Positive | 12 (2.0) | 15 (1.3) | 27 (1.5) |
No results | 69 (11.5) | 84 (7.1) | 153 (8.6) |