Skip to main content
Figure 3 | Malaria Journal

Figure 3

From: Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

Figure 3

Dissemination of malaria parasites in C57BL/6 wild-type (WT), CYP 2D knock-out, and humanized/CYP 2D6 knock-in mice 48 and 72 hr post-inoculation with luciferase expressing Plasmodium berghei in the absence or presence of tafenoquine. A (i-v). IVIS images of various mouse strains 48 and 72 hr post-inoculation. The mice of each group tested are shown and the corresponding luminescence signal indicated. B. Quantitated luminescence signal for each group tested 48 and 72 hr post-inoculation.

Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us