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Table 3 Diagnostic accuracy of Pf HRP2- compared to Pf -pLDH-detection

From: Accuracy of Pf HRP2 versus Pf-pLDH antigen detection by malaria rapid diagnostic tests in hospitalized children in a seasonal hyperendemic malaria transmission area in Burkina Faso

 

Pf HRP2

Pf-pLDH

p-value

RDT pos, n (%)

515 (74.2)

404 (54.2)

 

SE (95% CI)

100.0 (94.7 - 100.0)

98.7 (93.5-99.9)

1.0

Sp (95% CI)

70.9 (67.4 - 70.9)

94.0 (90.6 - 94.8)

< 0.001

PPV (95% CI)

69.4 (65.7 - 69.4)

91.6 (86.8 - 92.7)

< 0.001

NPV (95% CI)

100.0 (95.1 - 100.0)

99.1 (95.5 - 100.0)

1.0

  1. N = number, NPV = negative predictive value, Pf HRP2 = P. falciparum Histidine-rich protein-2, Pf-pLDH = P. falciparum- specific parasite lactate dehydrogenase pos = positive, PPV = positive, predictive value SE = sensitivity, Sp = specificity.
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Malaria Journal

ISSN: 1475-2875

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