Table 3 Sensitivity, specificity, predictive value and odds ratio of the haematological parameters in diagnosis of Malaria
From: Effect of malarial infection on haematological parameters in population near Thailand-Myanmar border
Variable | Sensitivity* (95% CI) | Specificity* (95% CI) | PPV* (95% CI) | NPV* (95% CI) | OR (95% CI) | PLR | NLR |
|---|---|---|---|---|---|---|---|
RBC <4×106/μL | 27 (24–31) | 86 (85–87) | 25 (22–28) | 88 (87–89) | 2.4 (2–2.9) | 2 | 0.8 |
Hb < 11 g/dL | 35 (32–39) | 68 (67–70) | 15 (14–17) | 87 (85–88) | 1.2 (1–1.4) | 1.1 | 0.9 |
MCV >100 fL | 1 (0.5–2) | 98 (97–99) | 10 (4–19) | 86 (85–87) | 0.7 (0.3–1.4) | 0.7 | 1 |
MCH >32 pg/cell | 3 (2–5) | 97 (96–97) | 13 (8–19) | 86 (85–87) | 0.9 (0.6–1.4) | 0.9 | 1 |
MCHC >37 g/dL | 2 (1–4) | 98 (98–99) | 18 (11–28) | 86 (85–87) | 1.4 (0.8–2.4) | 1.4 | 1 |
Platelets <150,000/μL | 85 (82–87) | 85 (84–86) | 48 (45–51) | 97 (96–98) | 31.8 (25.1–39.7) | 5.6 | 0.2 |
WBCs <4,000/μL | 17 (14–20) | 94 (93–94) | 30 (26–35) | 88 (87–89) | 3 (2.4–3.7) | 2.7 | 0.9 |
Neutrophils <2,800/μL | 35 (32–39) | 69 (68–70) | 16 (14–17) | 87 (86–89) | 1.2 (1.0–1.4) | 1.1 | 0.9 |
Lymphocytes <800/μL | 25 (23–28) | 78 (77–79) | 17 (15–19) | 86 (85–87) | 1.4 (1.1–1.6) | 1.2 | 1 |
Monocytes <80/μL | 3 (2–5) | 98 (97–99) | 19 (12–26) | 86 (85–87) | 1.4 (0.9–2.2) | 1.4 | 1 |
Eosinophils <40/μL | 27 (24–30) | 71 (69–72) | 13 (11–15) | 86 (84–87) | 0.9 (0.8–1) | 0.9 | 1 |
Basophils <16/μL | 89 (86–91) | 12 (11–13) | 14 (13–15) | 86 (83–89) | 1.0 (0.8–1.3) | 1 | 1 |
NL ratio >2.8 | 49 (45–52) | 61 (60–63) | 17 (15–19) | 88 (87–89) | 1.5 (1.3–1.8) | 1 | 0.8 |
ML ratio >0.25 | 58 (54–62) | 54 (53–56) | 17 (16–19) | 89 (88–90) | 1.7 (1.4–1.9) | 1.3 | 0.8 |