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Table 3 hQT time on day 0, 1 and 42 for children with and without positive urine sample of 4-aminoquinoline drugs

From: Disease-associated QT-shortage versus quinine associated QT-prolongation: age dependent ECG-effects in Ghanaian children with severe malaria

hQT (ms)

Day 0

Day 1

Day 42

P value1)day 1:0

P value1)day 42:0

P value1)day 42:1

4-aminoquinoline drugs negative

379 (±30) (n = 91)

408 (±32) (n = 91)

392 (±26) (n = 71)

<0.001

0.018

<0.001

4-aminoquinoline drugs positive

386 (±32) (n = 50)

401 (±32) (n = 50)

390 (±25) (n = 36)

<0.001

0.452

0.04

P value2) negative: positive

0.093

0.262

0.299

   
  1. Values are means (±SD) if not indicated otherwise. There was no difference in age between both groups.
  2. 1)Paired t-test.
  3. 2)Unpaired t-test.