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Table 4 Distribution of pfcrt , pfmdr1 and pvmdr1 point mutations in the investigated clinical isolates in Southern and Eastern Ethiopia

From: Return of chloroquine-sensitive Plasmodium falciparum parasites and emergence of chloroquine-resistant Plasmodium vivax in Ethiopia

 

P. falciparum

SE no

SE (%)

EE no

EE (%)

Pfcrt

only C72

5

2.9%

2

8.0%

 

C72 and K76

4

2.4%

1

4.0%

 

only K76

23

13.5%

8

32.0%

pfcrt and pfmdr1

K76 and N86

2

1.2%

2

8.0%

pfmdr1

only N86

22

12.9%

7

28.0%

 

N86 and Y184

6

3.5%

2

8.0%

 

only Y184

7

4.1%

3

12.0%

 

P. vivax

    

pvmdr1

only Y976

59

37.1%

11

19.6%

 

only F1076

0

  

0.0%

  1. pfmdr1: Plasmodium falciparum multi-drug resistance 1; pfcrt: Plasmodium falciparum chloroquine resistance transporter; pvmdr1: Plasmodium. vivax multi-drug resistance 1; SE: Southern Ethiopia; EE: Eastern Ethiopia.