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Figure 1 | Malaria Journal

Figure 1

From: A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway

Figure 1

Diagram of the coenzyme A synthesis pathway. The five enzymatic steps of CoA synthesis are highly conserved, however the amino acid sequences of the enzymes catalysing the reactions show low conservation between species. Identifiers of the putative P. falciparum enzymes are shown in brackets; * Essentiality of these putative P. falciparum enzymes is predicted in[6]; # Essentiality is predicted in[7].

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Malaria Journal

ISSN: 1475-2875

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