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Table 2 Number and proportion of samples positive for PfHRP2 antigen and anti-PfHRP2 antibody by ELISA

From: Circulating antibodies against Plasmodium falciparum histidine-rich proteins 2 interfere with antigen detection by rapid diagnostic tests

Sample type

Country

n

Antigen

Antibody

   

No

(%)

No

(%)

Acute patients (symptomatic & microscopy + ve)

Cambodia

15

14*

(100)*

3

(20.0)

 

Nigeria

23

21

(91.3)

8

(34.7)

 

Philippines

37

23

(62.2)

8

(21.6)

 

Sub-total

75

57

(76.0)

19

(25.3)

Asymptomatic (microscopy + ve or –ve)

Solomon Islands

28

6

(21.4)

3

(10.7)

Uninfected endemic controls

Nigeria

10

0

0

0

0

 

Philippines

8

0

0

2

(25)

Non-exposed controls

Brisbane

6

0

0

0

0

  1. *Antigen measured for 14 samples.