Table 1 Pooled prevalence of the various severity signs in studies with and without reported severe vivax malaria patients (140 studies)
From: Severe vivax malaria: a systematic review and meta-analysis of clinical studies since 1900
Complication | Total vivax | Total patients with severity sign | Pooled prevalence, % | 95% CI, % |
|---|---|---|---|---|
Death | 53164 | 353 | 0.1 | 0–0.2 |
Cerebral malaria | 52598 | 532 | 0.3 | 0.2–0.5 |
Multiple convulsions | 53139 | 88 | 0.17 | 0.13–0.2 |
Renal dysfunction | 53094 | 244 | 0.5 | 0–1 |
Respiratory dysfunction | 53164 | 144 | 0.27 | 0.23–0.32 |
Hepatic dysfunction | 53289 | 727 | 2 | 1.3–2.7 |
Abnormal bleeding/DIC | 53099 | 206 | 0.2 | 0–0.4 |
Haemoglobinuria | 53164 | 93 | 0.17 | 0.14–0.21 |
Hypoglycaemia | 53134 | 44 | 0.08 | 0.06–0.11 |
Metabolic acidosis | 53094 | 138 | 0.5 | 0–1.2 |
Circulatory collapse/Shock | 53164 | 67 | 0.1 | 0.01–0.16 |
Severe anaemia | 53164 | 2276 | 2 | 1.3–2.8 |
Severe thrombocytopenia | 52528 | 888 | 4.7 | 2.3–7 |