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Table 6 Final random effects model summarizing the significant, independent factors to explain the changes in the QTcB interval over time

From: Fixed dose artesunate amodiaquine – a phase IIb, randomized comparative trial with non-fixed artesunate amodiaquine

Effect Sex Estimate Standard error DF t Value Pr > |t|
Intercept   373.06 9.3613 52 39.85 <0.0001
Time   −0.016 0.00421 296 −3.8 0.0002
Age   0.4153 0.215 296 1.93 0.0543
Sex F 20.8761 4.6453 296 4.49 <0.0001
Sex M 0 . . . .
ECG heart rate   0.1461 0.06916 296 2.11 0.0355
DAQ concentrations   0.02972 0.01026 296 2.9 0.0041
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