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Table 2 Treatment endpoints on day 28, 42 after treatment and PCR adjusted day 42, Malakal, Upper Nile, Sudan, 2003–2004

From: Efficacy of two artemisinin combination therapies for uncomplicated falciparum malaria in children under 5 years, Malakal, Upper Nile, Sudan

 

AS + AQ

AS + SP

 

N

%

95% CI

N

%

95% CI

Day 28 Results

117

  

116

  

   ACPR

105

89.7

82.8–94.6

114

98.3

93.9 – 99.8

   ETF

0

0

 

1

0.9

0.0–4.7

   LCF

10

8.5

4.2–15.2

1

0.9

0.0–4.7

LPF

2

1.7

0.2–6.0

0

0

 

Day 42 Results

113

  

116

  

   ACPR

96

85.0

77.0–91.0

112

96.6

91.4–99.1

   ETF

0

0

 

1

0.9

0.0–4.7

   LCF

15

13.3

7.6–20.9

2

1.7

0.2–6.1

   LPF

2

1.8

0.2–6.2

1

0.9

0.0–4.7

PCR corrected day 42 #

97

  

113

  

No PCR result

(12)

  

(2)

  

Re-infections

(4)

  

(1)

  

   ACPR

96

99.0

94.4–100

112

99.1

95.2–100

   ETF

0

0

0.0–3.7

1

0.9

0.0–4.8

   LCF

1

1.0

0.0–5.6

0

0

0.0–3.2

   LPF

0

0

0.0–3.7

0

0

0.0–3.2

  1. #Cases with missing or undetermined PCR results and re-infections were excluded from the analysis. ACPR = Adequate Clinical Parasitological Response, ETF = Early Treatment Failure, LCF = Late Clinical Failure, LPF = Late Parasitological Failure.