Skip to main content

Table 4 Cytokine distribution in the Indian population: median TNF, IFN-γ and IL-10 per clinical group.

From: Total and functional parasite specific IgE responses in Plasmodium falciparum-infected patients exhibiting different clinical status

 

NEC (min-max)

EC (min-max)

UM (min-max)

SM (min-max)

CM (min-max)

ExCM (min-max)

TNF (pg/ml)

57 (39–73)

78 (63–120)

180 (119–207)

200 (173–381)

530 (258–1227)

81 (69–124)

IFN- γ (pg/ml)

23 (10–31)

22 (17–201)

119 (70–153)

127 (111–200)

65 (45–101)

32 (11–53)

IL-10 (pg/ml)

13 (5–26)

22 (11–31)

120 (97–147)

176 (121–253)

301 (175–506)

85 (40–108)

IL-4 (pg/ml)

18 (8–40)

58 (23–84)

65 (31–204)

69 (50–89)

62 (40–85)

48 (29–80)

  1. NEC – non endemic control, EC – endemic control, UM – uncomplicated malaria, SM – severe malaria (non-cerebral), CM – cerebral malaria, ExCM – Ex-cerebral malaria.
  2. Comparing group by group with the Endemic control: TNF was significantly lower in NEC (p = 0,0006) and higher in UM (p = 1,19 × 10-7), SM (p = 1,01 × 10-5) and CM (p = 2,26 × 10-7); IFN-γ was significantly higher in all diseased groups (UM – p = 5,11 × 10-6, SM – p = 1,01 × 10-6, CM – p = 9,71 × 10-6); IL-10 was significantly higher in all diseased groups (UM – p = 1,04 × 10-7, SM – p = 1,01 × 10-5 and CM – p = 2,46 × 10-7).
Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us