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Figure 7 | Malaria Journal

Figure 7

From: Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization

Figure 7

Effects of CRL1005 formulation on the magnitude of IFN-γ ELIspot responses in (A) Pf CSP/PBS versus Pf CSP/CRL1005 or (B) CSLAM/PBS versus CSLAM/CRL1005 immunized monkeys. Monkeys were immunized with either Pf CSP or CSLAM in PBS (open circle) or formulated in CRL1005 (solid circle). PBMC were collected at time points as defined in the legend to Figure 2 and assayed against recombinant P fCSP, Pf LSA1, Pf AMA1 or Pf MSP1 protein and Pf SSP2/TRAP peptide pools by IFN-γ ELIspot. Data represent the magnitude of IFN-γ responses specific for P fCSP, Pf SSP2/TRAP, Pf LSA1, Pf AMA1 or Pf MSP1, for each monkey.

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