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Table 2 Prevalence of pfcrt, pfmdr 1, dhfr and dhps genotype combinations conferring chloroquine and sulfadoxine-pyrimethamine resistance in Mbeya & Matema, together and each seperated. The risk ratio is the prevalence ratio of the combinations between Mbeya and Matema.

From: Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west Tanzania

Grouped alleles

     
  

Mbeya & Matema (%)

Mbeya (%)

Matema (%)

Risk ratio

Pfcrt+pfmdr1

T76+Y86**

29 (34.1)

9 (52.9)

20 (29.4)

0.5556

Dhfr

I51+N108*

80 (93)

17 (100)

63 (91.3)

0.9130

 

I51+R59*

71 (82.6)

16 (94.1)

55 (79.9)

0.8469

Dhfr triple

I51+R59+ N108*

71 (82.6)

16 (94.1)

55 (79.7)

0.8469

Dhps double

G437+E540***

68 (81)

10 (58.8)

58 (86.6)

1.4716

Dhfr/dhps quintuple (triple dhfr + double dhps) ***

54 (64.3)

9 (52.9)

45 (67.2)

1.2687

  1. * N = 86 ** N = 85 *** N = 84