Table 1 Characteristics of study subjects at enrollment
From: Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia
Characteristic | Amodiaquine/Placebo | Artesunate/Amodiaquine | |
|---|---|---|---|
N = 37 (%) | N = 34 (%) | ||
Age (years old) | Median | 19 | 18.5 |
Range | 5 to 62 | 3 to 58 | |
Gender | Male | 24 (64.8) | 27 (79.4) |
Female | 13 (35.2) | 7 (20.6) | |
Weight (kg) | Median | 55 | 57 |
Range | 19 to 99 | 12.5 to 80 | |
Temperature (°C) | Median | 36.6 | 36.6 |
Range | 35.9 to 39.0 | 36 to 40.2 | |
Parasitaemia (asexual forms/μL) | Geometric mean | 3420 | 4416 |
Range | 400 to 34,594 | 480 to 34,594 | |
Presence of gametocytes | Yes | 4 (10.8) | 8 (23.5) |
No | 33 (89.2) | 26 (76.5) | |
Haemoglobin (g/dL) | Median | 11,6 | 12 |
Range | 8.3 to 15.3 | 8.0 to 16.3 | |
WBC/mm3 | Median | 5900 | 5200 |
Range | 2200 to 12800 | 2000 to 15800 | |
Neutrophils/mm3 | Median | 3264 | 2900 |
Range | 1056 to 7134 | 1210 to 10428 | |
Total bilirubin (mg/dL) | Median | 1 | 1.3 |
Range | 0.2 to 5.3 | 0.1 to 5.2 | |
ALT (U/L) | Median | 24 | 24.2 |
Range | 2 to 98 | 5 to 107 | |
Creatinine (mg/dL) | Median | 0.9 | 1 |
Range | 0.4 to 1.9 | 0.4 to 1.4 | |