Skip to main content
Figure 2 | Malaria Journal

Figure 2

From: Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach

Figure 2

Illustrative example of a distribution of antimalarial susceptibility concentration-growth inhibition curves fitted using standard models. The most resistant isolate's curve fit is poor as inhibition was obtained only with the highest concentration tested (64 ng/mL), and so the EC50 derived using standard curve fitting lies at the mid-point (48 ng/mL) between the two highest concentrations tested (32 and 64 ng/mL). The Bayesian approach (dotted line) provides a lower estimate closer to the rest of the population.

Back to article page