Table 2 Parameter estimates obtained from fitting the 3-parameter sigmoid curve to the most resistant isolates using standard individual data analysis (fitted using WinNonlin®).
Isolate | Parameter estimates (% CV) | |||
|---|---|---|---|---|
|  | EC 50 | γ | Emax | EC 50 * |
Artesunate (A) | 23.3(22) | 12.5(65) | 0.95 (2) | 23.4 (12) |
Halofantrine (B) | 51.8(51564) | 27.9 (225370) | 1.10 (5) | 50.1 (37) |
Mefloquine (C) | 195 (4160) | 21.1 (25309) | 1.15 (2) | 175 (17) |
Mefloquine (D) | 197 (2014) | 17.1 (12967) | 1.25 (6) | 178 (52) |
Chloroquine (E) | 1065 (18) | 7.98 (68) | 0.79 (4.2) | 1065 (18) |
Chloroquine (F) | 536 (6) | 3.5 (18) | 0.92 (2.4) | 536 (6) |